Кафедра інфекційної патології, гігієни, санітарії та біобезпеки

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https://dspace.pdau.edu.ua/handle/123456789/5082

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Перегляд Кафедра інфекційної патології, гігієни, санітарії та біобезпеки за Автор "Dedukhno, A. V."

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    Публікація
    Comparative effectiveness of disinfectants used in vitro during embryogenesis of Toxocara cati nematodes
    (2026) Yevstafieva, V. O.; Євстаф’єва, Валентина Олександрівна; Perviy, A.; Melnychuk, V. V.; Мельничук, Віталій Васильович; Petrenko, M. O.; Петренко, Максим Олександрович; Kone, M. S.; Коне, Мохамед Сумана; Pishchalenko, M. A.; Піщаленко, Марина Анатоліївна; Dedukhno, A. V.; Дедухно, Алла Володимирівна; Krasota, O. G.; Красота, Олена Григорівна
    Toxocara cati helminths are widespread zoonotic pathogens that cause diseases in various wild and domestic animals, as well as humans, both definitive and paratenic hosts. Mature toxocaras release a significant number of eggs with the host’s feces, which pollute the external environment and are also resistant to adverse factors. To efficiently combat and prevent anthropozoonotic toxocariasis, it is necessary to carry out disinfestation using relevant agents. The aim of our research was to determine in laboratory conditions the ovicidal efficacy of disinfectants against embryogenesis of T. cati nematodes isolated from cats. It was found that the tested agents had different ovicidal efficacy on the test culture of T. cati eggs, depending on the composition of the disinfectant, its concentration and exposure. The most effective was "Iodine monochloride" (active ingredients include iodine monochloride and hydrochloric acid) at a concentration of 3.0%, which showed a high level of disinvasive action (96.7%) only after 60 min of exposure. The disinfectants "Dezirex Forte" (glutaraldehyde, benzalkonium chloride, didecyldimethylammonium chloride, N,N-didecyl-N-methyl- oly(oxyethyl)ammonium propionate, isopropanol), "Parvo-Virucide" (glutaraldehyde, benzyldimethyltetradecylammonium chloride) and "Multiclean Aqua" (benzalkonium chloride, didecyldimethylammonium chloride, glutaraldehyde, isopropanol, polyhexamethylene biguanide hydrochloride) showed satisfactory levels of ovicidal efficacy against T. cati eggs. The maximum values of the harmful effect were established for 2.0% "Dezirex Forte" at exposures of 30 and 60 minutes, 71.4 and 79.3%, respectively; 2.0% "Parvo-Virucide" at exposures of 30 and 60 minutes – 74.5 and 81.5%, respectively; 1.0% "Multiclean Aqua" at exposure of 60 minutes – 61.4%. Thus, we recommend the disinfectant "Iodine monochloride" under a certain regime for the effective neutralization of T. cati eggs and for the prevention of environmental contamination.