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Evaluation of effectiveness of disinfectants against exogenous stages of development of Nematodirus spathiger nematodes

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dc.contributor.authorYevstafieva, V. O.
dc.contributor.authorЄвстаф’єва, Валентина Олександрівна
dc.contributor.authorПономаренко, В. М.
dc.contributor.authorPonomarenko, V. M.
dc.contributor.authorMelnychuk, V. V.
dc.contributor.authorМельничук, Віталій Васильович
dc.contributor.authorSuprunenko, K. V.
dc.contributor.authorСупруненко, Костянтин Володимирович
dc.contributor.authorKarysheva, L. P.
dc.contributor.authorКаришева, Людмила Павлівна
dc.contributor.authorNikiforova, O.
dc.contributor.authorНікіфорова, О. В.
dc.contributor.authorKrykunova, V. E.
dc.contributor.authorКрикунова, Валентина Юхимівна
dc.contributor.authorMezhenska, N. A.
dc.contributor.authorМеженська, Н. А.
dc.date.issued2025
dc.description.abstractOne of the most common nematode diseases of ruminants is gastrointestinal strongyliasis. The pathogen’s life cycle partly occurs in the external environment. Its propagative stages are eggs secreted by infested animals, and invasive larvae, which persist in the environment for a long time and form biological pollution. Therefore, an integral part of the effective control and prevention of gastrointestinal strongyliasis of ruminants is the implementation of measures aimed at destroying pathogens in the environment to curb their potential distribution. The aim of the research was to investigate the disinvasive effectiveness of chemical preparations against eggs and invasive L3 larvae of the nematode Nematodirus spathiger, isolated from cattle, in laboratory conditions. It is established that the products "Hermecid-VS" (contains didecyldimethylammonium chloride, glutaraldehyde, benzalkonium chloride) and "Virosan" (contains benzalkonium chloride and glutaraldehyde) have ovicidal and larvicidal properties against exogenous stages of development of N. spathiger. At the same time, "Hermecid-VS" showed higher disinvasion activity compared to "Virosan". The ovicidal activity of disinfectants was higher than the larvicidal one. High levels of ovicidal efficacy were established when "Hermecid-VS" was used : 90.9% at a 0.1% concentration (exposure 60 min), and 100.0% at 0.25% and 0.5% concentrations (10–60 min). The larvicidal efficiency of "Hermecid-VS" was 90.7% at 0.25% concentration (60 min), and 95.3–100.0% at 0.5% concentration (10–60 min). The preparation "Virosan" showed a high level of ovicidal efficacy when used at a concentration of 0.25% (30–60 min) – 92.6–100.0%, at a concentration of 0.5% (10–60 min) – 100.0%, and a high level of larvicidal efficacy at a concentration of 0.5% (60 min) – 97.0%. The detrimental effect of disinfectants was characterized by morphological changes in the eggs and L3 larvae of N. spathiger, as well as in the metric parameters of N. spathiger eggs during their development. The obtained research results allow us to recommend the disinfectants "Hermecid-VS" and "Virosan" with the mentioned usage protocols to increase the effectiveness of prevention and treatment of N. spathiger infection in cattle
dc.identifier.citationYevstafieva V., Ponomarenko V., Melnychuk V., Suprunenko K., Karysheva L., Nikiforova O., Krykunova V., Mezhenska N. Evaluation of effectiveness of disinfectants against exogenous stages of development of Nematodirus spathiger nematodes. Regulatory Mechanisms in Biosystems. 2025. № 16 (3). e25127. DOI: https://doi.org/10.15421/0225127
dc.identifier.urihttps://dspace.pdau.edu.ua/handle/123456789/19604
dc.language.isoen
dc.subjectnematodirosis
dc.subjectcattle
dc.subjectnematode eggs
dc.subjectinvasive larva
dc.subjectdisinfestation
dc.subjectovocidal efficiency
dc.titleEvaluation of effectiveness of disinfectants against exogenous stages of development of Nematodirus spathiger nematodes
dc.typeArticle
dspace.entity.typePublication
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Друковані видання. Кафедра паразитології та ветеринарно-санітарної експертизи