Друковані видання. Кафедра паразитології та ветеринарно-санітарної експертизи

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https://dspace.pdau.edu.ua/handle/123456789/5089

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Перегляд Друковані видання. Кафедра паразитології та ветеринарно-санітарної експертизи за Ключові слова "cats"

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  • Ескіз
    Публікація
    Influence of Ctenocephalides felis on biochemical indicators of blood serum of infested cats
    (2025) Гаврик, Б. А.; Мельничук, Віталій Васильович; Melnychuk, V. V.; Havryk, B. А.
    Fleas represent one of the most important groups of blood-sucking parasitic insects. An important aspect of the medical and veterinary importance of fleas, which has not lost its relevance even today, is their role in maintaining natural foci of zooanthroponotic and zoonotic infections. With constant flea attacks on an animal, clinical signs develop, characterized by itching, anxiety, and dermatopathologies, which are due to certain parasite-host relationships, which are based on the interaction of the pathogenic effect of the parasite and the host's defense mechanism. The aim of the research was to determine changes in the biochemical parameters of blood serum of infested cats at different levels of ctenocephalic invasion intensity. The conducted studies have established that flea parasitism on the body of cats led to a negative impact of ectoparasites on the biochemical parameters of the blood serum of infested cats. With increasing intensity of flea infestation of cats, the severity of changes in the biochemical parameters of their blood serum increased. Thus, at low levels of ctenocephalic invasion intensity (up to 19 specimens/head), a decrease in albumin content by 3.99 % (p<0.05) was detected in the blood serum of infected cats compared to the levels in clinically healthy cats. All other indicators were within physiological fluctuations. At higher rates of intensity of ctenocephalic invasion (from 20 to 42 specimens/head) in the blood serum of infected cats, a decrease in albumin content by 15.39 % (p<0.01), glucose by 35.99 % (p<0.05), an increase in total bilirubin content by 33.54 % (p<0.05), urea by 36.24 % (p<0.05), creatinine by 16.18 % (p<0.05), as well as an increase in the activity of enzymes alanine aminotransferase by 22.42 % (p<0.05), aspartate aminotransferase by 38.56 % (p<0.05), alkaline phosphatase by 2.4 times (p<0.05), α-Amylase by 51.44 % (p<0.05), gamma-glutamyl transpeptidase by 31.22 % (p<0.05) compared to the indicators in clinically healthy cats. The results obtained expand existing data on the impact of fleas on the body of infested cats, and also allow us to take into account indicators of infestation intensity in increasing the effectiveness of treatment measures
  • Ескіз
    Публікація
    Molecular and sequencing study of Otodectes cynotis in cats in Karbala province/Iraq
    (2026) Alali, F.; Jassem, M. I.; Alsheikh, S. M.; Jawad, M.; Melnychuk, V. V.; Мельничук, Віталій Васильович
    Background: Otodectes cynotis is an obligate ectoparasite and a major cause of otodectosis (ear mange) in domestic and wild animals, particularly cats. Aims: This study aimed to determine the prevalence of O. cynotis infestation among cats in Karbala province, Iraq, evaluate associated demographic/risk factors, and perform molecular characterization and phylogenetic analysis of local isolates. Methods: Ear swab samples were collected from 187 cats presenting at the Teaching Animal Hospital of Kerbala University. Diagnosis was confirmed using otoscopic and microscopic examinations. Polymerase chain reaction (PCR) targeting the rDNA internal transcribed spacer 1 (ITS-1) region was performed on 10 isolates from three cat breeds (Sherazi, Himalayan, and Scottish). The PCR products (570 bp) were sequenced and analyzed using BioEdit, ClustalW, and MEGA software (Neighbor-Joining method). Results: The overall prevalence of O. cynotis was 46% (86/187). Statistical analysis showed no significant association between infestation rates and season, sex, body weight, or breed ($p > 0.05$), though age was significantly associated with infection, showing the highest prevalence in kittens under one year old ($p = 0.036$). Pruritus was the predominant clinical sign (90.7%). Sequencing revealed two novel Iraqi genotypes submitted to GenBank under accession numbers PV123832 and PV564189. Phylogenetic analysis demonstrated close genetic clustering between the novel isolates, reference strain HQ728005.1, and canine isolate KP676677.1. Conclusion: Otodectes cynotis is highly prevalent among domestic cats in Karbala, with young animals being particularly vulnerable. The high genetic similarity between cat- and dog-derived isolates emphasizes low host specificity, highlighting the need for continuous molecular surveillance to control potential mite outbreaks and transmission.